Table of Contents FDA Requests Removal of Opana ER for Risks Related to Abuse Abuse and Manipulation of Opana ER Resources and References: Today, the U.S. Food and Drug Administration requested that Endo Pharmaceuticals remove its opioid pain medicine, reformulated Opana ER (oxymorphone hydrochloride), from the market. After careful consideration, the agency is seeking removal…
Table of Contents Chronic Pain Is an Impossible Problem Neurontin Prescription Resources and References: A “safe” alternative to opioid painkillers turns out to be unsafe. Neurontin was supposed to be the answer. Chronic pain afflicts about a fifth of American adults, and for years, physicians thought it could be treated with prescription painkillers like Oxycontin.…
Nembutal, its scientific name being pentobarbital, is a barbiturate tranquillizer that has numerous applications in the field of medicine. It is mainly used to treat sleeplessness and preoperative anxiety, which allows patients to be anesthetized. Nembutal’s efficacy in depressing the central nervous system enables it to be used as a brief measure against insomnia by…
Nardil (Phenelzine sulfate) is a widely used antidepressant that falls under the category of monoamine oxidase inhibitors (MAOIs). It is often prescribed for treating various forms of severe depression, especially atypical, non-endogenous, or neurotic depression, and cases where other antidepressants have failed. However, recent manufacturing problems have led to significant supply issues, posing challenges for…
Table of Contents Morphine Sulfate Addiction How Does Morphine sulfate Work? What Are The Signs Of Morphine Addiction? Resources and References: Morphine Sulfate (the sulfate salt of morphine), an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine, derived from the poppy plant, is one of the most powerful narcotic opioids that…
Table of Contents How Morphabond Makes Abuse by Smoking Difficult Resources and References: A team of Ohio researchers found that a novel formulation of extended-release (ER) morphine sulfate, MorphaBond ER (Daiichi Sankyo, Inspirion Delivery Sciences), is unlikely to be abused via smoking, largely due to the high degradation of its active ingredient when burned. A common…
The world’s favorite smart drug is much safer than Adderall and a promising treatment for substance abuse and neurodegenerative disorders—so why can’t we use it? Chances are you’ve heard of the drug modafinil. You know the one: the “smart drug,” sometimes called the “Limitless” pill, that turns sleep-deprived college students and young professionals into energetic workhorses.…
Methylphenidate, known as Methylin, is a drug that has been prescribed mainly for attention deficit hyperactivity disorder (ADHD) and narcolepsy treatment. It acts like a stimulant to the central nervous system in the brain, thus enabling it to balance neurotransmitters, which can improve focus and lessen impulsiveness in persons with ADHD. Methylin is typically given…
Table of Contents Meth Addiction and Estrogen Resources and References: Male rats have held steady as the focus of most addiction studies in the past. But as the field starts to take female rats into account, scientists see that drugs like methamphetamine affect the sexes separately, suggesting the basis for a change in addiction treatment.…
Table of Contents Methadose Use and Addiction Life-threatening Respiratory Depression Life-Threatening QT Prolongation Accidental Ingestion Misuse, Abuse, and Diversion of Opioids Interactions with Drugs Affecting Cytochrome P450 Isoenzymes Mechanism of Action Resources and References: Life-threatening Respiratory Depression Respiratory depression, including lethal cases, has been reported during the initiation and conversion of patients to Methadose. Even…
